You must have a strategy going into a game is as important as the strategy and goals you have set for your life. To be taken seriously in Online Texas Hold' em Poker as in life, you must appear to be in control and seem like you know what you're doing. Also you must know the tips.
It's time to play hands that you would not normally play when the players are 4 or 5. This is required as the blinds are typically higher and you must protect your blinds. Whenever you're not in a blind, however, it's advisable to hang back and only play really good starting hands that you're confident in. If you can avoid it, this is not a time to go "fishing" for a draw.
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Playing anywhere you may want to have the loose aggressive players to your right and tight passive players to your left. You will see a raise coming before calling the first bet, having such position. If the game is tight enough that it is being folded around to the blinds often. Then you want some very tight passive players in the two seats to your right, so that your blinds will not be stolen. Choosing a right seat considered to be the most important skill just because a good table and the winning seat is a pledge of victory.
You should be holding a good hand, a worthy draw, or you believe that your bluff can win the pot, if you are still in the game at the turn.
Also if you over-call, you want to make sure you have a good enough hand to win over legitimate calling hands.
Poker is a game of skill, but it is also a game of chance. Try to learn from any mistakes you made and chalk up losing sessions to bad luck. Don't expect to win every time you play.